Overwhelming evidence indicates that virtually all treatment-naive tumors contain a subpopulation of cancer cells that possess some stem cell traits and properties and are operationally defined as cancer cell stem cells (CSCs).CSCs manifest inherent heterogeneity in that they may exist in an epithelial and proliferative state or a mesenchymal non-p

MORN5 (MORN repeat containing 5) is encoded by a locus positioned on chromosome 17 in the chicken genome.The MORN motif is found in multiple copies in several proteins including junctophilins or phosphatidylinositol phosphate kinase family and the MORN proteins themselves are found across the animal and plant kingdoms.MORN5 protein has a characteri

Starting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always following a rigorous scientific in-depth analysis.This section of the Journal, Review Notes, is a continuous update about emerging topics concerning relationships among urban planning, mobility, and envir

Deubiquitinating enzymes (DUBs) are proteases that control the post-translational modification of proteins by ubiquitin and in turn regulate diverse cellular pathways.Despite a growing understanding of DUB biology at the structural and molecular level, little is known about the physiological importance of most DUBs.Here, we systematically identify